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1

Pharmacokinetics and Safety of Velpatasvir and Sofosbuvir/Velpatasvir in Subjects with Hepatic Impairment

Mogalian, Erik, Brainard, Diana M., Osinusi, Anu, Moorehead, Lisa, Murray, Bernard, Ling, Kah Hiing John, Perry, Robert, Curtis, Craig, Lawitz, Eric, Lasseter, Kenneth, Marbury, Thomas, Mathias, Anita

Journal:

Clinical Pharmacokinetics

Year:

2018

Language:

english

File:

PDF, 726 KB

english, 2018

2

Using Stepwise Pharmacogenomics and Proteomics to Predict Hepatitis C Treatment Response in Difficult to Treat Patient Populations

Naggie, Susanna, Clement, Meredith, Lusk, Sam, Osinusi, Anu, Himmel, Tiffany, Lucas, Joseph E., Thompson, Will J., Dubois, Laura, Moseley, M. Arthur, Clark, Paul J., Kottilil, Shyam, Patel, Keyur

Journal:

PROTEOMICS - Clinical Applications

Year:

2018

Language:

english

File:

PDF, 896 KB

english, 2018

3

Mycobacterium tuberculosis and Mycobacterium africanum in stools from children attending an immunization clinic in Ibadan, Nigeria

S.I.B. Cadmus, A.O. Jenkins, J. Godfroid, K. Osinusi, I.F. Adewole, R.L. Murphy, B.O. Taiwo

Journal:

International Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 167 KB

english, 2009

4

Long-Term Outcome of Second-Line Antiretroviral Therapy in Resource-Limited Settings

Osinusi-Adekanmbi, O., Stafford, K., Ukpaka, A., Salami, D., Ajayi, S., Ndembi, N., Abimiku, A., Nwizu, C., Gilliam, B., Redfield, R., Amoroso, A.

Journal:

Journal of the International Association of Providers of AIDS Care (JIAPAC)

Year:

2014

Language:

english

File:

PDF, 186 KB

english, 2014

5

Comparative efficacy, pharmacokinetic, pharmacodynamic activity, and interferon stimulated gene expression of different interferon formulations in HIV/HCV genotype-1 infected patients

Osinusi, Anu, Bon, Dimitra, Nelson, Amy, Lee, Yu-Jin, Poonia, Seerat, Shivakumar, Bhavana, Cai, Shu Yi, Wood, Brad, Haagmans, Bart, Lempicki, Richard, Herrmann, Eva, Sneller, Michael, Polis, Michael,

Journal:

Journal of Medical Virology

Year:

2014

Language:

english

File:

PDF, 581 KB

english, 2014

6

Virologic Response Following Combined Ledipasvir and Sofosbuvir Administration in Patients With HCV Genotype 1 and HIV Co-infection

Osinusi, Anu, Townsend, Kerry, Kohli, Anita, Nelson, Amy, Seamon, Cassie, Meissner, Eric G., Bon, Dimitra, Silk, Rachel, Gross, Chloe, Price, Angie, Sajadi, Mohammad, Sidharthan, Sreetha, Sims, Zayani

Journal:

JAMA The Journal of the American Medical Association

Year:

2015

Language:

english

File:

PDF, 323 KB

english, 2015

7

Etiologic Agents and Outcome Determinants of Community-Acquired Pneumonia in Urban Children: A Hospital-Based Study

Johnson, Abdul-Wahab B.R., Osinusi, Kikelomo, Aderele, Wilson I., Gbadero, Daniel A., Olaleye, Olufemi D., Adeyemi-Doro, Folorunsho A.B.

Journal:

Journal of the National Medical Association

Year:

2008

Language:

english

File:

PDF, 1.47 MB

english, 2008

8

Drug-Drug Interactions Studies between HCV Antivirals Sofosbuvir/Velpatasvir and Boosted and Unboosted HIV Antiretroviral Regimens in Healthy Volunteers

Mogalian, Erik, Stamm, Luisa M, Osinusi, Anu, Brainard, Diana M, Shen, Gong, Ling, Kah Hiing John, Mathias, Anita

Journal:

Clinical Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 487 KB

english, 2018

9

Ledipasvir/Sofosbuvir for 12 weeks is safe and effective in adolescents with chronic hepatitis C virus infection and hematological malignancies undergoing chemotherapy

El-Sayed, M.H., Ebeid, F.S.E.S., Zekri, A.R., Massetto, B., Kersey, K., Osinusi, A., Zhang, F., Brainard, D., Elsayed, W., El-Haddad, A.

Journal:

Journal of Hepatology

Year:

2018

Language:

english

File:

PDF, 50 KB

english, 2018

10

Successes and challenges of under-five child mortality reduction in West Africa

Umar, LW, Osinusi, K

Journal:

Nigerian Journal of Paediatrics

Year:

2014

Language:

english

File:

PDF, 1.64 MB

english, 2014

11

Acute bronchiolitis in tropical Africa: A hospital-based perspective in Ibadan, Nigeria

Abdul-Wahab B.R. Johnson, Wilson I. Aderele, K. Osinusi, Daniel A. Gbadero, A.H. Fagbami, N.A. Rotowa

Journal:

Pediatric Pulmonology

Year:

1996

Language:

english

File:

PDF, 1006 KB

english, 1996

12

Prevalence and clinical pattern of paediatric HIV infection at the University College Hospital, Ibadan, Nigeria: a prospective cross-sectional study

Babatunde O Ogunbosi, Regina E Oladokun, Biobele J Brown, Kikelomo I Osinusi

Journal:

Italian Journal of Pediatrics

Year:

2011

Language:

english

File:

PDF, 185 KB

english, 2011

13

REPRODUCIBILITY OF BIPARIETAL DIAMETER MEASUREMENTS OBTAINED WITH A REAL-TIME SCANNER

B. O. Osinusi, A. J. Hall, A. H. Adam, J. E. E. Fleming

Journal:

BJOG: An International Journal of Obstetrics & Gynaecology

Year:

1980

Language:

english

File:

PDF, 284 KB

english, 1980

14

Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response

Susanna Naggie, Anu Osinusi, Antonios Katsounas, Richard Lempicki, Eva Herrmann, Alexander J. Thompson, Paul J. Clark, Keyur Patel, Andrew J. Muir, John G. McHutchison, Joerg F. Schlaak, Martin Trippl

Journal:

Year:

2012

Language:

english

File:

PDF, 717 KB

english, 2012

15

ITPA gene polymorphisms significantly affect hemoglobin decline and treatment outcomes in patients coinfected with HIV and HCV

Anu Osinusi, Susanna Naggie, Seerat Poonia, Martin Trippler, Zonghui Hu, Emily Funk, Joerg Schlaak, Dawn Fishbein, Henry Masur, Michael Polis, Shyam Kottilil

Journal:

Journal of Medical Virology

Year:

2012

Language:

english

File:

PDF, 303 KB

english, 2012

16

IL28B polymorphism is not associated with HCV protease diversity in patients co-infected with HIV and HCV treated with pegylated interferon and ribavirin

Anu Osinusi, Aarthi Chary, Mark A. Winters, Susanna Naggie, Henry Masur, Michael A. Polis, Shyam Kottilil, Mark Holodniy

Journal:

Journal of Medical Virology

Year:

2012

Language:

english

File:

PDF, 87 KB

english, 2012

17

Infectious Diseases in Under-five Children in Kano, North-western Nigeria

F. Hassan-Hanga, K. Osinusi, M. Ibrahim

Journal:

International Journal of Infectious Diseases

Year:

2008

Language:

english

File:

PDF, 50 KB

english, 2008

18

17β-estradiol, progesterone and testosterone in the normal menstrual cycle of Nigerians

O.A. Dada, B.O. Osinusi, E.U. Nduka, B.O. Osotimehin, O.A. Ladipo

Journal:

International Journal of Gynecology & Obstetrics

Year:

1984

Language:

english

File:

PDF, 406 KB

english, 1984

19

Homozygous sickle cell anemia at the University College Hospital, Ibadan, revisited

B.O. Osinusi, J.A. Adeleye

Journal:

International Journal of Gynecology & Obstetrics

Year:

1989

Language:

english

File:

PDF, 497 KB

english, 1989

20

Neonatal Mortality in an Urban Population in Ibadan, Nigeria

Anthony O. Adetola, Olukemi O. Tongo, Adebola E. Orimadegun, Kike Osinusi

Journal:

Pediatrics & Neonatology

Year:

2011

Language:

english

File:

PDF, 180 KB

english, 2011

21

Sofosbuvir and Ribavirin for Hepatitis C Genotype 1 in Patients With Unfavorable Treatment Characteristics

Osinusi, Anuoluwapo, Meissner, Eric G., Lee, Yu-Jin, Bon, Dimitra, Heytens, Laura, Nelson, Amy, Sneller, Michael, Kohli, Anita, Barrett, Lisa, Proschan, Michael, Herrmann, Eva, Shivakumar, Bhavana, Gu

Journal:

JAMA The Journal of the American Medical Association

Year:

2013

Language:

english

File:

PDF, 294 KB

english, 2013

22

IFNL4- G Genotype Is Associated With Slower Viral Clearance in Hepatitis C, Genotype-1 Patients Treated With Sofosbuvir and Ribavirin

Meissner, E. G., Bon, D., Prokunina-Olsson, L., Tang, W., Masur, H., O'Brien, T. R., Herrmann, E., Kottilil, S., Osinusi, A.

Journal:

The Journal of Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 206 KB

english, 2014

23

Dependability of B-scan and real time measurements by a newly trained operator

Osinusi, B.O., Hall, A.J., Adam, A.H., Fleming, J.E.E.

Journal:

Ultrasound in Medicine & Biology

Year:

1981

Language:

english

File:

PDF, 247 KB

english, 1981

24

1 ALTERED HCV SPECIFIC T CELL IMMUNITY VERY EARLY IN INTERFERON FREE HCV DAA THERAPY

Barrett, L., Shivasabesan, G., Wang, C., Osinusi, A., Kohli, A., Meissner, E.G., Heytens, L., Nelson, A., Polis, M.A., Masur, H., Symonds, W., McHutchinson, J., Kottilil, S.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 184 KB

english, 2013

25

O14 USE OF SOFOSBUVIR/LEDIPASVIR FIXED DOSE COMBINATION FOR TREATMENT OF HCV GENOTYPE-1 IN PATIENTS COINFECTED WITH HIV

Osinusi, A., Townsend, K., Nelson, A., Kohli, A., Gross, C., Polis, M.A., Pang, P.S., Symonds, W.T., Talwani, R., Sajadi, M.M., Hogan, J., Benator, D., Subramanian, M., Mchutchison, J., Masur, H., Kot

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 102 KB

english, 2014

26

P578 Appraisal of menstrual awareness among female secondary school girls in Lagos

Tayo, A., Akinola, O., Shittu, L., Ottun, T., Osinusi, D.

Journal:

International Journal of Gynecology & Obstetrics

Year:

2009

Language:

english

File:

PDF, 50 KB

english, 2009

27

O11 RETREATMENT OF RELAPSERS TO SOFOSBUVIR/RIBAVIRIN WITH SOFOSBUVIR/LEDIPASVIR: COMPLETE AND RAPID VIROLOGIC SUPPRESSION BY WEEK 4

Osinusi, A., Marti, M., Townsend, K., Nelson, A., Kohli, A., Silk, R., Pang, P., Symonds, W.T., McHutchison, J., Masur, H., Kottilil, S.

Journal:

Journal of Hepatology

Year:

2014

Language:

english

File:

PDF, 78 KB

english, 2014

28

Comparison of socio-demographic and clinical characteristics of orphans and non-orphans among HIV-positive children in Ibadan, Nigeria

Oladokun, Regina, Brown, Biobele, Aiyetan, Paul, Ayodele, Olulade, Osinusi, Kikelomo

Journal:

International Journal of Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 153 KB

english, 2009

29

1428 INVERSE CHANGES IN HEPATIC EXPRESSION OF INTERFERON LAMBDA AND ALPHA AND IFNL4 GENOTYPE ARE ASSOCIATED WITH TREATMENT RESPONSE IN SOFOSBUVIR/RIBAVIRIN TREATED HCV GENOTYPE-1 SUBJECTS

Meissner, E.G., Bon, D., Osinusi, A., Tang, W., Herrmann, E., McHutchison, J., Symonds, W., Masur, H., O'Brien, T.R., Prokunina-Olsson, L., Kottilil, S.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 463 KB

english, 2013

30

Boceprevir for HCV in patients with HIV: where next?

Osinusi, Anuoluwapo, Naggie, Susanna

Journal:

The Lancet Infectious Diseases

Year:

2013

Language:

english

File:

PDF, 209 KB

english, 2013

31

1334 DYSREGULATION OF HOST INNATE IMMUNITY IN HCV GENOTYPE 1 INFECTED IL28B CT/TT HAPLOTYPE PATIENTS WITH DEPRESSED VIRAL KINETICS AND THERAPEUTIC RESPONSE

Naggie, S., Osinusi, A., Katsounas, A., Lempicki, R., Herrmann, E., Shivakumar, B., Thompson, A., Clark, P., Patel, K., Muir, A., Mchutchison, J., Goldstein, D., Schlaak, J., Masur, H., Polis, M., Kot

Journal:

Journal of Hepatology

Year:

2011

Language:

english

File:

PDF, 127 KB

english, 2011

32

1187 PK–PD MODELING IN A SUB-GROUP OF PATIENTS TREATED WITH GS-7977 AND RIBAVIRIN SHOWED A SIGNIFICANTLY SLOWER EARLY VIRAL KINETICS IN RELAPSERS

Bon, D., Herrmann, E., Shivakumar, B., Lee, Y.-J., Heytens, L., Polis, M., Masur, H., Neumann, A.U., Symonds, W.T., McHutchison, J., Kottilil, S., Osinusi, A.

Journal:

Journal of Hepatology

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

33

Interleukin-23 Promotes Interferon-α Responsiveness in Hepatitis C Virus/HIV-Coinfected Patients

Odigie, Madeline, Osinusi, Anu, Barrett, Lisa, Townsend, Kerry, Wang, Honghui, Suffredini, Anthony F., Masur, Henry, Polis, Michael A., Kottilil, Shyam

Journal:

AIDS Research and Human Retroviruses

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

34

Rapid Development of Advanced Liver Fibrosis after Acquisition of Hepatitis C Infection during Primary HIV Infection

Osinusi, Anu, Kleiner, David, Wood, Brad, Polis, Michael, Masur, Henry, Kottilil, Shyam

Journal:

AIDS PATIENT CARE and STDs

Year:

2009

Language:

english

File:

PDF, 8.94 MB

english, 2009

35

Favorable adverse event profile of sofosbuvir/ribavirin compared to boceprevir/interferon/ribavirin for treatment of hepatitis C

Narayanan, Shivakumar, Townsend, Kerry, Macharia, Thomas, Majid, Adrian, Nelson, Amy, Redfield, Robert R., Kottilil, Shyam, Talwani, Rohit, Osinusi, Anu

Journal:

Hepatology International

Year:

2014

Language:

english

File:

PDF, 465 KB

english, 2014

36

Disclosure of HIV status to infected children in a Nigerian HIV Care Programme

Brown, Biobele J., Oladokun, Regina E., Osinusi, Kikelomo, Ochigbo, Sunny, Adewole, Isaac F., Kanki, Phyllis

Journal:

Year:

2011

Language:

english

File:

PDF, 268 KB

english, 2011

37

Infant-feeding pattern of HIV-positive women in a prevention of mother-to-child transmission (PMTCT) programme

Oladokun, Regina E., Brown, Biobele J., Osinusi, Kikelomo

Journal:

Year:

2010

Language:

english

File:

PDF, 133 KB

english, 2010

38

Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study

Kohli, Anita, Osinusi, Anuoluwapo, Sims, Zayani, Nelson, Amy, Meissner, Eric G, Barrett, Lisa L, Bon, Dimitra, Marti, Miriam M, Silk, Rachel, Kotb, Colleen, Gross, Chloe, Jolley, Tim A, Sidharthan, Sr

Journal:

Year:

2015

Language:

english

File:

PDF, 279 KB

english, 2015

39

Utility of Hepatitis C Viral Load Monitoring on Direct-Acting Antiviral Therapy

Sidharthan, S., Kohli, A., Sims, Z., Nelson, A., Osinusi, A., Masur, H., Kottilil, S.

Journal:

Clinical Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 1.31 MB

english, 2015

40

Effect of sofosbuvir and ribavirin treatment on peripheral and hepatic lipid metabolism in chronic hepatitis C virus, genotype 1-infected patients

Meissner, Eric G., Lee, Yu-Jin, Osinusi, Anu, Sims, Zayani, Qin, Jing, Sturdevant, Dan, McHutchison, John, Subramanian, Mani, Sampson, Maureen, Naggie, Susanna, Patel, Keyur, Remaley, Alan T., Masur,

Journal:

Year:

2015

Language:

english

File:

PDF, 996 KB

english, 2015

41

Comparison of auditory brainstem response in HIV-1 exposed and unexposed newborns and correlation with the maternal viral load and CD4+ cell counts

Fasunla, Ayotunde James, Ogunbosi, Babatunde Oluwatosin, Odaibo, Georgina Njideka, Nwaorgu, Onyekwere George Benjamin, Taiwo, Babafemi, Olaleye, David Olufemi, Osinusi, Kikelomo, Murphy, Robert Leo, A

Journal:

Year:

2014

Language:

english

File:

PDF, 257 KB

english, 2014

42

Clinical and Immunological Profile of Pediatric HIV Infection in Ibadan, Nigeria

Brown, B. J., Oladokun, R. E., Odaibo, G. N., Olaleye, D. O., Osinusi, K., Kanki, P.

Journal:

Journal of the International Association of Physicians in AIDS Care (JIAPAC)

Year:

2011

Language:

english

File:

PDF, 107 KB

english, 2011

43

Sustained Virologic Response for Chronic Hepatitis C Infection After 27 Days of Treatment with Sofosbuvir and Ribavirin

Meissner, E. G., Nelson, A., Marti, M., Masur, H., Osinusi, A., Kottilil, S.

Journal:

Open Forum Infectious Diseases

Year:

2014

Language:

english

File:

PDF, 167 KB

english, 2014

44

HIV/AIDS in 3 Generations: Case Series

Oladokun, R. E., Adejokun, E., Brown, B. J., Osinusi, K.

Journal:

Journal of the International Association of Physicians in AIDS Care (JIAPAC)

Year:

2010

Language:

english

File:

PDF, 155 KB

english, 2010

45

Serum and cellular ribavirin pharmacokinetic and concentration–effect analysis in HCV patients receiving sofosbuvir plus ribavirin

Rower, Joseph E., Meissner, Eric G., Jimmerson, Leah C., Osinusi, Anu, Sims, Zayani, Petersen, Tess, Bushman, Lane R., Wolfe, Pamela, McHutchison, John G., Kottilil, Shyamasundaran, Kiser, Jennifer J.

Journal:

Journal of Antimicrobial Chemotherapy

Year:

2015

Language:

english

File:

PDF, 314 KB

english, 2015

46

Effect of HIV on Liver Fibrosis Among HCV-Infected African Americans

Silver, D., Karnik, G., Osinusi, A., Silk, R., Stabinski, L., Doonquah, L., Henn, S., Teferi, G., Masur, H., Kottilil, S., Fishbein, D.

Journal:

Clinical Infectious Diseases

Year:

2013

Language:

english

File:

PDF, 92 KB

english, 2013

47

Urinary tract infection in febrile children with sickle cell anaemia in Ibadan, Nigeria

Asinobi, A. O., Fatunde, O. J., Brown, B. J., Osinusi, K., Fasina, N. A.

Journal:

Annals of Tropical Paediatrics International Child Health

Year:

2003

Language:

english

File:

PDF, 100 KB

english, 2003

48

Acute Respiratory Tract Infection in Children in Idikan Community, Ibadan, Nigeria: Severity, Risk Factors, and Frequency of Occurrence

Oyejide, C. O., Osinusi, K.

Journal:

Clinical Infectious Diseases

Year:

1990

Language:

english

File:

PDF, 457 KB

english, 1990

49

Child Care Practices with Respect to Acute Respiratory nact Infection in a Poor, Urban Community in Nigeria

Osinusi, K., Oyejide, C. O.

Journal:

Clinical Infectious Diseases

Year:

1990

Language:

english

File:

PDF, 250 KB

english, 1990

50

Bacterial Aetiology of Acute Lower Respiratory Infections in Pre-School Nigerian Children and Comparative Predictive Features of Bacteraemic and Non-Bacteraemic Illnesses

Johnson, A-W. B. R., Osinusi, K., Aderele, W. I., Adeyemi-Doro, F. A. B.

Journal:

Journal of Tropical Pediatrics

Year:

1993

Language:

english

File:

PDF, 715 KB

english, 1993